(2008) Large genomic deletions of SMAD4, BMPR1A and PTEN in juvenile polyposis. Gut 57: 623-627. Alazzouzi H, Alhopuro P, Salovaara R, Sammalkorpi H, Järvinen H, et al. (2005) SMAD4 as a prognostic marker in colorectal cancer. ...
However, the molecular mechanisms underlying the low expression of PTEN in lung fibroblasts in IPF remain to be determined. Xia et al hypothesized that caveolin-1, a molecule involved in cell signaling and intake of external molecules ...
Knockdown of PTEN expression using small interfering RNA specific for PTEN in PC-9 cells resulted in drug resistance to gefitinib and erlotinib. Nuclear translocation of the EGR1 transcription factor, which regulates PTEN expression, ...
